6-Aminocaproic acid

CAS No. 60-32-2

6-Aminocaproic acid( ε-Aminocaproic Acid | EACA | NSC 26154 | NSC 212532 | NSC 400230 )

Catalog No. M15254 CAS No. 60-32-2

6-Aminocaproic acid is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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100MG 58 In Stock
200MG 84 In Stock
500MG 138 In Stock
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Biological Information

  • Product Name
    6-Aminocaproic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    6-Aminocaproic acid is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
  • Description
    6-Aminocaproic acid is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.(In Vitro):6-Aminocaproic acid (20-180 μg/mL) inhibits fibrinolysis in plasma of Asian elephants, with an effective concentration of 61.5 μg/mL.6-Aminocaproic acid can be used as a hydrophobic linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green.(In Vivo):6-Aminocaproic acid (20-100 mg/kg; a single p.o.) inhibits fibrinolysis at all doses tested in dogs.6-Aminocaproic acid (20-100 mg/kg; a single p.o.) is rapidly absorbed (Tmax=1 h) and eliminated rapidly in dogs.
  • In Vitro
    6-Aminocaproic acid (20-180 μg/mL) inhibits fibrinolysis in plasma of Asian elephants, with an effective concentration of 61.5 μg/mL.6-Aminocaproic acid can be used as a hydrophobic linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green.
  • In Vivo
    6-Aminocaproic acid (20-100 mg/kg; a single p.o.) inhibits fibrinolysis at all doses tested in dogs.6-Aminocaproic acid (20-100 mg/kg; a single p.o.) is rapidly absorbed (Tmax=1 h) and eliminated rapidly in dogs.
  • Synonyms
    ε-Aminocaproic Acid | EACA | NSC 26154 | NSC 212532 | NSC 400230
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Plasminogen
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    60-32-2
  • Formula Weight
    131.18
  • Molecular Formula
    C6H13NO2
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 1 mg/mL (7.62 mM); Water: 26 mg/mL (198.21 mM); DMSO: 6 mg/mL (45.74 mM)
  • SMILES
    O=C(O)CCCCCN
  • Chemical Name
    Aminocaproic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mochalkin I, et al. Biochemistry. 1999 Feb 16;38(7):1990-8.
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